In short
Synthetic growth hormone-releasing peptides whose study led to the discovery of the natural hormone ghrelin. Not authorized in Canada.
Also known asgrowth hormone-releasing peptides
CategoryGrowth hormone
Canada statusNot authorized in Canada
Human evidence Limited: small or low-quality human studies
Sport (WADA)WADA's Prohibited List bans growth hormone releasing factors and secretagogues (S2) at all times.
Last reviewedNovember 10, 2026
How strong is the human evidence?
- Cell & animal
- Small human studies
- Some randomized trials
- Large randomized trials
What is GHRP-2 and GHRP-6?
GHRPs are small synthetic peptides that trigger GH release through the receptor later found to respond to ghrelin. Cyril Bowers, who developed them, reviewed this history (1998, 2001).
GHRP-6 is known for increasing appetite. Both are sold online as "research peptides".
Is GHRP-2 and GHRP-6 legal in Canada?
Not authorized: no products found in the Drug Product Database.
What the research shows
- Human pharmacology studies show acute GH release (reviewed by Bowers 1998; Ghigo et al. 1997).
What it doesn't show
- No randomized trials showing muscle, fat-loss or recovery benefits in healthy adults.
Common questions
GHRP-2 vs GHRP-6?
Both release GH; GHRP-6 is more associated with hunger. Neither is authorized in Canada.
Are GHRPs legal in Canada?
They are not authorized by Health Canada.
Sources
- Bowers CY. Growth hormone-releasing peptide (GHRP). Cell Mol Life Sci 1998
- Bowers CY. Unnatural growth hormone-releasing peptide begets natural ghrelin. JCEM 2001
- Ghigo E et al. Growth hormone-releasing peptides. Eur J Endocrinol 1997
- Health Canada Drug Product Database (searched Nov 10, 2026)
- World Anti-Doping Agency — Prohibited List