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Brain & sleep

Selank

Not authorized in Canada Evidence 2/4
Selank peptide structure illustration (abstract amino-acid chain)
In short

A Russian-developed nasal peptide studied for anxiety, mainly as an add-on to a benzodiazepine. Not authorized in Canada.

Reviewed November 10, 2026 · 3 sources cited below

Also known astuftsin analog
Canada statusNot authorized in Canada
Human evidence Limited: small or low-quality human studies
Last reviewedNovember 10, 2026

How strong is the human evidence?

Limited: small or low-quality human studies. How we rate evidence

What is Selank?

Selank is a synthetic analog of tuftsin, a small immune-related peptide. It was developed in Russia.

What the research shows

  • Medvedev et al. (2015, Russian): in 70 patients with anxiety disorders, adding selank to phenazepam was reported to speed the effect and reduce side effects compared with phenazepam alone.
  • Rat studies report anti-anxiety effects (e.g. Kasian et al. 2017).

What it doesn't show

  • No large independent trials of selank on its own; no evidence for stress or focus use in healthy people.

Common questions

Is selank legal in Canada?

It is not authorized by Health Canada.

Does selank work for anxiety?

Small Russian studies suggest possible benefit as an add-on; independent high-quality trials are lacking.

Sources

  1. Health Canada Drug Product Database (searched Nov 10, 2026)
  2. Medvedev VE et al. Optimization of the treatment of anxiety disorders with selank. Zh Nevrol Psikhiatr 2015
  3. Kasian A et al. Selank enhances diazepam's effect in reducing anxiety in rats. Behav Neurol 2017

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