In short
A natural hormone that switches on the reproductive axis. Researchers have tested it as an IVF trigger in small trials. Not authorized in Canada.
Also known askisspeptin-10, kisspeptin-54
CategorySexual health
Canada statusNot authorized in Canada
Human evidence Limited: small or low-quality human studies (fertility research)
Last reviewedNovember 10, 2026
How strong is the human evidence?
- Cell & animal
- Small human studies
- Some randomized trials
- Large randomized trials
What is Kisspeptin?
Kisspeptins are natural peptides that act upstream of GnRH and are central to puberty and fertility.
Is Kisspeptin legal in Canada?
Not authorized: no product found in Health Canada's Drug Product Database.
What the research shows
- Abbara et al. (JCEM 2015): in 60 women at high risk of ovarian hyperstimulation syndrome undergoing IVF, a single kisspeptin-54 injection triggered egg maturation in 95%.
What it doesn't show
- No approved use; no evidence for libido or testosterone "optimization" in healthy people.
Common questions
Is kisspeptin legal in Canada?
It is not authorized by Health Canada.
Does kisspeptin raise testosterone?
It stimulates the reproductive hormone axis in research settings, but it isn't an approved treatment for low testosterone.
Sources
- Health Canada Drug Product Database (searched Nov 10, 2026)
- Abbara A et al. Kisspeptin-54 to trigger oocyte maturation in women at high risk of OHSS. JCEM 2015
- Sharma B et al. Use of kisspeptin to trigger oocyte maturation during IVF. Front Endocrinol 2022
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