Canada Peptide Guide
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Sexual health

Sexual & reproductive health peptides

PT-141, melanotan, kisspeptin and oxytocin: from an FDA-approved drug to unauthorized tanning injections.

4 peptides1 authorized in Canada3 not authorized / other
Sexual health peptides: illustration
PT-141 (Bremelanotide) peptide illustrationPT-141 (Bremelanotide)A melanocortin-receptor drug approved by the FDA in 2019 as Vyleesi for low sexual desire in premenopausal women. We…Not authorized in Canada (approved elsewhere)Melanotan I and II peptide illustrationMelanotan I and II"Tanning peptides" sold online. Health Canada lists melanotan I and II among seized unauthorized injectables. A…Not authorized in CanadaKisspeptin peptide illustrationKisspeptinA natural hormone that switches on the reproductive axis. Researchers have tested it as an IVF trigger in small trials.…Not authorized in CanadaOxytocin peptide illustrationOxytocinA peptide hormone authorized in Canada as an injection used in labour and delivery. Intranasal oxytocin for social or…Authorized in Canada (prescription)

Evidence at a glance

How many peptides in this category reach each level of human evidence (our rating, see each page for sources).

Large randomized trials1
Some randomized trials1
Small human studies1
Cell & animal only1

Status and evidence table

PeptideCanada statusHuman evidence
PT-141 (Bremelanotide)Not authorized in Canada (approved elsewhere) Moderate: some randomized human trials, specific uses (small effects)
Melanotan I and IINot authorized in Canada Melanotan II: case reports of harm only; afamelanotide: RCTs in a rare disease
KisspeptinNot authorized in Canada Limited: small or low-quality human studies (fertility research)
OxytocinAuthorized in Canada (prescription) Established for obstetric use; inconclusive for intranasal social/mood uses
Status reflects Health Canada's peptide pages, its April 2026 advisory and the Drug Product Database as checked on November 10, 2026. Authorized products carry an 8-digit DIN (drugs) or NPN (natural health products).